
Many people with chronic pain develop mental illness, such as depression or anxiety, as a result of their pain. This article, however, will discuss those who have mental illness onset before developing chronic pain.
Research Study
A 2022 study by Johnston and Huckins, found that almost all psychiatric conditions listed in the DSM-5 are associated with increased rates of chronic pain. (The DSM-5 is short for the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition and is the standard reference book published by the American Psychiatric Association in 2013. It gives mental health experts clear lists of signs and symptoms to diagnose mental health conditions.)
The Connection Between Mind and Pain
While mental illness does not cause chronic pain directly, the two conditions are interconnected and the former can lower your pain threshold, amplify how your brain processes physical discomfort, and cause physical tension that results in persistent aches. Below are four ways the mind and pain can be connected:
- Shared Brain Pathways: Physical pain and emotional distress (such as anxiety and depression) process through overlapping neural circuits and chemical messengers in the brain.
- Altered Pain Perception: Conditions like depression can change how the central nervous system interprets signals, making ordinary physical sensations feel significantly more painful.
- Physical Tension and Stress: Chronic mental stress causes sustained muscle tension, leading to recurring physical discomfort like tension headaches or lower back pain.
- Sleep Disruption: Mental health disorders frequently disrupt sleep, and a lack of restorative sleep impairs the body’s natural ability to manage and recover from pain.
Is there hope for those who have mental illness and chronic pain?
Yes there is! Research shows that treating them together, rather than separately, can significantly improve daily life, lower distress, and reduce pain signals. This is often accomplished in the following ways:
- Combined Medications: Certain medicines, such as specific antidepressants, help manage both chronic pain and mood disorders by targeting shared chemical messengers.
- Targeted Talk Therapy: Approaches like Cognitive Behavioral Therapy (CBT) and Acceptance and Commitment Therapy (ACT) teach practical skills to lower the nervous system’s threat response and change how the brain processes discomfort.
- Multidisciplinary Care: Comprehensive pain rehabilitation programs bring medical, physical, and psychological experts together to build a single, manageable recovery plan.
- Mind-Body Strategies: Mindfulness, gentle movement, and specialized nervous-system regulation techniques help break the cycle of ongoing physical and emotional stress.
Do you have mental illness and chronic pain? Have you found strategies that have worked to alleviate the symptoms of the chronic pain?








